Several advanced options exist to take caching to the next level in Drupal. With advanced caching Drupal is able to scale to levels required by the most demanding of sites.
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Custom Drupal Distributions (part 10)
There are a couple of projects which have made it easy to achieve performance gains by making slight amendments to core or packaging up the code in a helpful manner. Pressflow makes it possible to use a reverse proxy such as Varnish, amongst other things. Mercury packages Pressflow up as a Amazon EC2 image. The [...]